Blogs about: Nuclear Receptor

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Repros announce completion of Phase II enrollment in Proellex trial

crimsoncanary wrote 1 month ago: Repros Therapeutics have announced that they now have sufficient patients currently enrolled to prov … more →

Tags: Proellex, repros, Progenta, progesterone, phase ii, Repros Therapeutics

PregLem initiate Phase III trial of SPRM PGL-4001

crimsoncanary wrote 1 month ago: PregLem have announced that it is initiating a Phase III trial of its selective progesterone recepto … more →

Tags: progesterone, phase iii, PregLem, sprm, PGL-4001, ulipristal, PGL4001

Seretide®/Advair treatment effective in COPD

crimsoncanary wrote 1 month ago: Study results show that treatment with Seretide/Advair (salmeterol/fluticasone propionate ) slows … more →

Tags: agonist, fluticasone, Beta 2 adrenoceptor, advair, G.ks, salmeterol

Eprotirome effective in Phase II trial

crimsoncanary wrote 2 months ago: Karo Bio has successfully completed a 12 week phase IIb study of thyroid receptor agonist eprotirome … more →

Tags: agonist, phase ii, thyroid, Phase IIb, Eprotirome, Karo Bio, KB-141, KB141

GTx Announce Phase III Clinical Development of Toremifene on Course

crimsoncanary wrote 2 months ago: GTx have announced that phase III trials of toremifene are on course following a planned safety revi … more →

Tags: estrogen, serm, toremifene, Fareston

EU recommends approval of Basileas Toctino (alitretinoin)

crimsoncanary wrote 2 months ago: Basilea Pharmaceutica has announced that Toctino (alitretinoin) has been recommended for approval fo … more →

Tags: rar, agonist, Regulatory, approval, Basilea, Toctino, Alitretinoin, BAL-4079, BAL4079

Hollis-Eden initiate Phase I/II trial of Apoptone in Prostate Cancer

crimsoncanary wrote 2 months ago: Hollis-Eden has commenced a Phase I/II clinical trial with its oral drug candidate Apoptone  (HE323 … more →

Tags: androgen, Antagonist, Apoptone, he-3235, HE3235, Hollis-Eden, Phase I, phase ii

Proellex shows no potential for tumor induction in a 2 year study

crimsoncanary wrote 2 months ago: Repros Therapeutics have released data frm a two-year study conducted to determine Proellex … more →

Tags: Proellex, repros, Progenta, progesterone, Repros Therapeutics

Differin Gel approced in Japan for Acne

crimsoncanary wrote 2 months ago: Galderma Pharma have announced that Japan’s Ministry of Health, Labor and Welfare has approve … more →

Tags: agonist, Adapalene, Differin, Adaferin, Redap, Retinoic acid beta receptor, RAR beta, Galderma, Shionogi

Mometasone approved in Japan for Allergic Rhinitis

crimsoncanary wrote 2 months ago: Schering-Plough has received marketing approval in Japan for Nasonex (mometasone furoate monohydrate … more →

Tags: Glucocorticoid receptor, Glucocorticoid, Regulatory, approval, Mometasone, Schering-Plough, nasonex

Proellex shows no adverse effects in long term treatment of Uterine Fibroids

crimsoncanary wrote 2 months ago: Repros Therapeutics have announced that Proellex was found to be safe in the chronic treatment of th … more →

Tags: Proellex, repros, Progenta, progesterone, Repros Therapeutics

Proellex significantly reduces pain in severe Endometriosis

crimsoncanary wrote 2 months ago: Repros Therapeutics have announced that Phase II data show its Progesterone antagonist Proellex to s … more →

Tags: Proellex, repros, Progenta, progesterone, Repros Therapeutics

SkyePharmas Third Flutiform Phase III Study meets endpoints

crimsoncanary wrote 3 months ago: SkyePharma have announced that its third Phase III trial of Flutiform in asthma patients has met its … more →

Tags: agonist, Glucocorticoid, SkyePharma, Flutiform, phase iii, Abbott, Mundipharma, Kyorin, Beta 2 adrenoceptor

FDA approves Sirion Therapeutics Durezol for postoperative ocular inflammation and pain

crimsoncanary wrote 3 months ago: The FDA has approved Sirion Therapeutics’ topical steroid Durezol for the treatment of postoperat … more →

Tags: Glucocorticoid, Regulatory, Sirion, Durezol, difluprednate, approval

DuoCort hydrocortisone gets orphan drug designation for adrenal insufficiency

crimsoncanary wrote 3 months ago: DuoCort’s hydrocortisone dual-release oral tablet has been given orphan drug status for the tr … more →

Tags: Regulatory, hydrocortisone, DuoCort, FDA

Nippon Shinyaku grants Yoo Young rights to NS-126 in Korea

crimsoncanary wrote 3 months ago: Nippon Shinyaku have granted Yoo Young Pharmaceutical rights to its once daily steroid drug NS-126 f … more →

Tags: Licensing, Nippon Shinyaku, Yoo Young NS-126, NS126

Repros Therapeutics initiate Phase IIb study of Androxal

crimsoncanary wrote 3 months ago: Repros Therapeutics have initiated a phase IIb clinical study to monitor the effects of Repro … more →

Tags: agonist, repros, phase ii, androgen, Testosterone, enclomid, enclomiphene, Phase IIb, Repros Therapeutics

Alizyme has granted an exclusive licence to Norgine for the rights to COLAL-PRED for Ulcerative Colitis

crimsoncanary wrote 3 months ago: Alizyme has granted an exclusive licence to Norgine for the rights to COLAL-PRED in the treatment an … more →

Tags: Glucocorticoid receptor, Glucocorticoid, Prednisolone, Alizyme, COLAL-PRED, norgine, Licensing

Rosiglitazone delays the onset of Proliferative Diabetic Retinopathy

crimsoncanary wrote 3 months ago: Data publsihed in the Archives of Ophthalmology show that rosiglitazone has been found to delay the … more →

Tags: GSK, GlaxoSmithKline, rosiglitazone, AVANDIA, Venvia


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