Blogs about: Ion Channel
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Anesiva insitate Phase II trual of Adlea in Arthroscopic Shoulder Surgery
Anesiva have begun a Phase II clinical trial of Adlea, the company’s long-acting capsaicin product in for the management of acute pain in patients undergoing arthroscopic shoulder surgery involving … more »
Ion channel News
Anesiva insitate Phase II trual of Adlea in Arthroscopic Shoulder Surgery
crimsoncanary wrote 1 week ago: Anesiva have begun a Phase II clinical trial of Adlea, the company’s long-acting capsaicin product … more »
NeurogesX Initiate Phase I of NGX-1998 Capsaicin Liquid Formulation
crimsoncanary wrote 1 week ago: NeurogesX has initiated a Phase 1 clinical trial of NGX-1998, a high-concentration, capsaicin-based … more »
Vertexs VX-770 improves lung function in cystic fibrosis
crimsoncanary wrote 1 month ago: Data presentes at the 31st European Cystic Fibrosis Society Meeting shows Vertex’s VX-770 to i … more »
AstraZeneca and Cellectricon collaborate on Dynaflow High Throughput Ion Channel Screening
crimsoncanary wrote 1 month ago: AstraZeneca have expanded their collaboration with Cellectricon. AstraZeneca will install two Dynafl … more »
Inspire’s Denufosol shows efficacy in Phase III trials in Cystic Fibrosis
crimsoncanary wrote 1 month ago: Inspire’s denufosol inhalation solution has shown efficacy in Phase III trials in Cystic Fibrosis. … more »
Phase II trials of Adlea in post orthopedic surgery pain to take place in South Korea
crimsoncanary wrote 1 month ago: Anesiva to begin Phase II trial of Capsaicin drug Adlea for use in the treatment of post orthopedic … more »
NeurogesX submit IND for liquid formulation of Capsaicin, NGX-1998
crimsoncanary wrote 1 month ago: NeurogesX have submitted an IND for the liquid formulation of Capsaicin, NGX-1998 for the treatment … more »
US and WO patent update for the week ending 05/23
crimsoncanary wrote 2 months ago: US and WO ion channel patents have been updated for this week at IonChannelCentral.com … more »
TRPV4 Channel Agonist GSK1016790A Induces Urinary Bladder Contraction and Hyperactivity
crimsoncanary wrote 2 months ago: GSK’s transient receptor potential vanilloid 4 (TRPV4) agonist GSK1016790A contracts mouse bla … more »
Dendreons TRPM8 modulator D3263 shows promise in BPH
crimsoncanary wrote 2 months ago: Dendreon’s TRPM8 modulator D-3263 has been shown to reduce prostate weight by 39% in an anima … more »
Amitiza (lubiprostone) relieves IBS in Phase III
crimsoncanary wrote 2 months ago: Chloride channel agonist Amitiza (lubiprostone) had been shown to significantly relieve symptoms of … more »
YM-758 pharmacokinetics in rats and humans
crimsoncanary wrote 2 months ago: The hepatic uptake and excretion of YM-758 is otlined in a Drug Metabolism and Disposition paper. Y … more »
US and WO patent update for the week ending 05/16
crimsoncanary wrote 2 months ago: US and WO ion channel patents have been updated for this week at IonChannelCentral.com … more »
Azor shows efficacy in difficult to treat patient groups
crimsoncanary wrote 2 months ago: Data presented at ASH shows that Azor (amlodipine and olmesartan medoxomil) safely and effectively l … more »
Exforge treatment effective in black patients
crimsoncanary wrote 2 months ago: Black patients treated with Exforge (Amlodipine/Valsartan) have been show to experience a significan … more »
NHE-1 inhibitors shift Sodium channels into the inactive state
crimsoncanary wrote 2 months ago: Pfizer scientists report that NHE-1 inhibitors may to reduce peripheral neuronal excitability by shi … more »
Forest and Daiichi Sankyo end Azor co promotion agreement
crimsoncanary wrote 2 months ago: Forest has terminated it’s co-promotion agreement for Azor (amlodipine and olmesartan medoxomi … more »
Icagen report on Ion Channel Progress
crimsoncanary wrote 2 months ago: ICA-105665 KCNQ channel opener for epilepsy - Single ascending dose Phase I trial completed; multipl … more »
Elocalcitol increases Ca2+ entry and L-type Calcium expression
crimsoncanary wrote 2 months ago: Vitamin D3 analog Elocalcitol has been found to upregulate Ca2+ entry through L-type Ca2+ channels. … more »
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