Blogs about: Drug Interactions

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Drug Interactions6 comments

tungtide wrote 2 weeks ago: We have been a little light on posts over here so I thought I would bounce a post up that has to do … more »

Tags: Answers, birth control, CYP3A4, Drug Development, drug metabolism, opioids, P450, Pharmacology, st johns wort

Drug Interactions of Oral Contraceptives

joesterheld wrote 1 month ago: COMMENT: The drug interactions of oral contraceptives (OCs) are quite complex. They are both a victi … more »

Tags: Personalized Medicine, Cytochrome P450

Herb-Drug Interactions

joesterheld wrote 2 months ago: COMMENT: H. canadensis (goldenseal or Golden Seal, a perennial  of the buttercup family), otherwise … more »

Tags: Cytochrome P450, Personalized Medicine, Add new tag, cytochrome P450 2D6, herbal interactions

The role of hepatic transporters in drug elimination

DNADiva wrote 2 months ago: COMMENT: This article helps develop a picture of hepatic cells transporters, both the ABC and the SL … more »

Tags: Personalized Medicine, drug elimination, drug transporters, transporters

Interview with a Pharmacist

currligirl wrote 2 months ago: Hi Everyone, I couldn’t possibly write anything better than this.  Go to www.dearpharmacist.c … more »

Tags: health, drugs, Medicines, Pharmaceuticals, Pills

OATP Knock Out Murine Model

DNADiva wrote 2 months ago: COMMENT: The mutant in vivo mouse model or the so-called “knock out” (ko) mouse in which … more »

Tags: Cytochrome P450, Personalized Medicine, pharmacogenetics, drug metabolism, inducer, inhibitor, OATP, pravastatinsubstrate, rifampin

Desipramine / Bupropion Clinical Drug-Drug Interaction

DNADiva wrote 3 months ago: COMMENT: The fact that desipramine levels were doubled with the addition of bupropion was a surprisi … more »

Tags: Cytochrome P450, Personalized Medicine, bupropion, CYP, CYP2D6, Desipramine, Drug-Drug Interaction

Medication Management

jstreed wrote 3 months ago: Hundreds of thousands of people go to the emergency room every year because of problems with medic … more »

Tags: Men's Health, Women's Health, All Audio, Mayo clinic, Podcast, Podcasts, Odell, Medications, Management

Science magazine fuels DNA testing controvery with prejudicial misquote3 comments

DNADiva wrote 3 months ago: There is a policy comment due out in Science today in which Genelex’s website is prejudicially quo … more »

Tags: Cytochrome P450, Personalized Medicine, pharmacogenetics, Consumer-Driven Healthcare, consumer right, CYP, DNA, P4 medicine, P450

Pharmacokinetic Interaction Between Tadalafil and Bosentan in Healthy Male Subjects

DNADiva wrote 3 months ago: COMMENT: Combinations of agents are being tried for pulmonary arterial hypertension (PAH)- a serious … more »

Tags: Personalized Medicine, Cytochrome P450, CYP3A4, CYP, päh!, tadalafil, bosentan, phosphodiesterase, endothelin receptor antagonist

Drug-drug interactions in a geriatric outpatient cohort

DNADiva wrote 3 months ago: COMMENT: This article speaks to the clinical significance of drug interactions in a particularly sus … more »

Tags: Personalized Medicine, Drug-drug, Geriatrics, elderly, DDI, ADR

Pharmacokinetic interactions between contraceptives and antiepileptic drugs

DNADiva wrote 4 months ago: COMMENT: This is a short review of an important subject especially for psychiatrists and neurologist … more »

Tags: Cytochrome P450, Personalized Medicine, antiepileptics, Contraceptives, CYP3A4, inducers, Pharmacokinetics

Baclofen (Oral Route)

Bonnie wrote 4 months ago: Description Baclofen is used to help relax certain muscles in your body. It relieves the spasms, cra … more »

Tags: MS, Baclofen, muscle relaxant

ABC drug transporters as molecular targets for the prevention of multidrug resistance and drug-drug interactions

DNADiva wrote 4 months ago: COMMENT: Research about the ABC transporters has been skyrocketing in the last 3 years. These transp … more »

Tags: Personalized Medicine, abc, drug transporters, p-glycoprotein

Frequency and clinical relevance of drug interactions with lovastatin and simvastatin : an observational database study

DNADiva wrote 4 months ago: COMMENT:: Although clinicians should be aware of potential drug interactions with the statins that a … more »

Tags: Personalized Medicine, Cytochrome P450, CYP3A4, Lovastatin, simvastatin

Inhibitory effects of fruit juices on CYP3A activity

DNADiva wrote 4 months ago: COMMENT: This pair of articles highlights the importance of not relying on invitro data in predictin … more »

Tags: Cytochrome P450, Personalized Medicine, 3A4, ADRs, CYP3A, cytochromes

Update on Rifampin and Rifabutin Drug Interactions

DNADiva wrote 5 months ago: COMMENT:: Review of this area is important since in many parts of the world, rifampin is the only dr … more »

Tags: Personalized Medicine, Cytochrome P450

Herbal and dietary supplement--drug interactions in patients with chronic illnesses.

DNADiva wrote 5 months ago: Dr. Oesterheld’s Comment: This article reviews an important drug interaction area. I generally ag … more »

Tags: Cytochrome P450, Personalized Medicine, st johns wort, herbals, Supplements

Assessment of drug-drug interaction for silymarin

DNADiva wrote 5 months ago: Dr Oesterheld’s Comment: Silymarin (aka silibinin, silybin) is an extract of milk thistle, an ant … more »

Tags: Cytochrome P450, Personalized Medicine, pharmacogenetics, 3A4, CYP, Cytochrome, Interactions, pharamcogenetics. cytochrome p450, silymarin


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