Blogs about: Cdk
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Sunesis publish modified SNS-032 analogs
Sunesis have published a series of modified SNS-032 analogs … more →
Kinase News
Sunesis publish modified SNS-032 analogs
crimsoncanary wrote 1 week ago: Sunesis have published a series of modified SNS-032 analogs … more →
Postcards from Vienna...
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kinasepro wrote 1 week ago: Hey look what I got: Yah, its the disclosure of the discovery of PHA-848125. Not only that, its a … more →
GSK publish seres of CDK inhibitors
crimsoncanary wrote 2 weeks ago: GSK have published a series of pyrazolo[1,5-b]pyridazine CDK inhibitors … more →
Sunesis publish diaminocyclohexyl analog of SNS-032
crimsoncanary wrote 2 weeks ago: Sunesis have published the discovery of a diaminocyclohexyl analog of CDK inhibitor SNS-032 that has … more →
Faster Substructure Search in the CDK
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Rajarshi Guha wrote 3 weeks ago: The CDK uses the UniversalIsomorphismTester to perform graph and subgraph isomorphism. However it … more →
Cyclacel refocuses on non kinase projects
crimsoncanary wrote 3 weeks ago: Cyclacel to focus resources on the advancement of its lead drug, sapacitabine. Workforce to be reduc … more →
Faster Fingerprinting
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Rajarshi Guha wrote 4 weeks ago: In my last post I had reported some timing measurements for various operations. One of them was fing … more →
CDK Performance Measurements
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Rajarshi Guha wrote 4 weeks ago: As part of a larger project, I’ve been doing some profiling on various aspects of the CDK, foc … more →
AstraZeneca publish series of cyclin-dependent kinase inhibitors
crimsoncanary wrote 1 month ago: AstraZeneca have published a series of Imidazole cyclin-dependent kinase (CDK) inhibitors … more →
Nightly Build Site for CDK 1.2.x
Rajarshi Guha wrote 1 month ago: Since we’re coming up to a 1.2 release (see Egons post) I’ve put up a nightly build site … more →
Test Coverage Report for CDK Nightly
Rajarshi Guha wrote 1 month ago: I just updated the CDK Nightly build script so that it summarizes the state of unit test coverage. C … more →
Researchers publish Roscovitine derived CDK/CK1 inhibitors
crimsoncanary wrote 1 month ago: Researchers from Univ Paris, CNRS, Univ Athens and Rockefeller Univ have published a series of Rosco … more →
Schering Plough initiate Phase I trial of CDK inhibitor SCH-727965 in breast cancer
crimsoncanary wrote 1 month ago: Schering Plough have initiated a phase I trial of CDK 1/2/9 inhibitor SCH 727965 in patients with … more →
AstraZeneca publish discovery of Imidazole piperazine CDK inhibitors
crimsoncanary wrote 2 months ago: AstraZeneca have published the synthesis fo a series of imidazole piperazine cyclin-dependent … more →
Coadministration of CDK inhibitor seliciclib with EGFR inhibitors increases activity
crimsoncanary wrote 3 months ago: Studies published by Cyclacel on the coadministration of CDK inhibitor seliciclib with EGFR/HER2 inh … more →
Fragmenter2.java
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genetical wrote 4 months ago: So I’ve been trying to play around with this program called “Fragmenter2.java,” wh … more →
Sunesis to cut workforce by 60% to concentrate on Voreloxin
crimsoncanary wrote 4 months ago: Sunesis are cutting 60% of its workforce to concentrate on development of its lead compound voreloxi … more →
GPC-Biotechs CDK inhibitor RGB-286638 active in vitro
crimsoncanary wrote 4 months ago: Data presented at ASCO show GPC-Biotech’s CDK inhibitor RGB-286638 to cause multiple myeloma c … more →
Cyclacel initiate Phase I combination study of Seliciclib and Tarceva
crimsoncanary wrote 4 months ago: Cyclacel and the Vall d’Hebron University Hospital have initiated a Phase I trial of Cyclacel … more →
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